Tabriz University of Medical Sciences Journal of Cardiovascular and Thoracic Research 2008-5117 7 3 2015 09 02 Right Valsalva Sinus Aneurysm Protruding Into the Right Ventricle: A Case Report 126 128 10.15171/jcvtr.2015.27 EN Ata H. Afshar Sergei Kolesnikov Leili Pourafkari Nader D. Nader Journal Article 10.15171/jcvtr.2015.27 2015 07 23 A separation between the aortic media and annulus fibrosus causes a rare cardiac abnormality called sinus of Valsalva aneurysm (SVA) that may be congenital or acquired. It is more prevalent in the right coronary sinus (65%-85%) but it has been seen rarely in non-coronary (10%-30%)or Left coronary sinus (<5%). The most common complication is rupture of the Aneurysm. We present an 80-year-old male with expanding right Valsalva sinus aneurysm and protruding into right ventricle. The conventional treatment is surgical repair under cardio-pulmonary bypass or percutaneous catheter closure. The aneurysm was successfully excised surgically under direct guidance of trans-esophageal echocardiography (TEE).