Tabriz University of Medical Sciences Journal of Cardiovascular and Thoracic Research 2008-5117 8 1 2016 03 17 Device closure in adults with atrial septal defect in Shiraz, a single center registry 40 42 10.15171/jcvtr.2016.07 EN Mohammad Ali Ostovan Javad Kojuri Pooyan Dehghani Vida Razazi Alireza Moarref Journal Article 10.15171/jcvtr.2016.07 2015 09 02 2015 11 23 Introduction: Successful closure of atrial septal defect (ASD) improves patients’ functional class and exercise capacity. In this study we evaluate the safety and feasibility of percutaneous device closure of ASDs. Methods: Two hundred fifty six patients with significant ASD according to our criteria were enrolled. The patients were treated using nitinol wire mesh transcatheter devices. Complications were followed for a median of 2.5 years. Results: Success rate was 98.4% with 3 unsuccessful cases and a mean hospital stay of 1.007 ± 0.0004 days. Complication rate was 7.42%. Size of the right ventricle (RV) annulus was significantly decreased 24 hours after intervention (P = 0.005). Conclusion: The present report demonstrates that transcatheter closure of ASD is safe and effective.