﻿<?xml version="1.0" encoding="UTF-8"?>
<ArticleSet>
  <Article>
    <Journal>
      <PublisherName>Tabriz University of Medical Sciences</PublisherName>
      <JournalTitle>Journal of Cardiovascular and Thoracic Research</JournalTitle>
      <Issn>2008-5117</Issn>
      <Volume>12</Volume>
      <Issue>4</Issue>
      <PubDate PubStatus="ppublish">
        <Year>2020</Year>
        <Month>12</Month>
        <DAY>16</DAY>
      </PubDate>
    </Journal>
    <ArticleTitle>In-hospital and short-term predictors of mortality in patients with intermediate-high risk pulmonary embolism</ArticleTitle>
    <FirstPage>321</FirstPage>
    <LastPage>327</LastPage>
    <ELocationID EIdType="doi">10.34172/jcvtr.2020.51</ELocationID>
    <Language>EN</Language>
    <AuthorList>
      <Author>
        <FirstName>Gulay</FirstName>
        <LastName>Gök</LastName>
        <Identifier Source="ORCID">https://orcid.org/0000-0003-0205-1138</Identifier>
      </Author>
      <Author>
        <FirstName>Mehmet</FirstName>
        <LastName>Karadağ</LastName>
      </Author>
      <Author>
        <FirstName>Tufan</FirstName>
        <LastName>Çinar</LastName>
        <Identifier Source="ORCID">https://orcid.org/0000-0001-8188-5020</Identifier>
      </Author>
      <Author>
        <FirstName>Zekeriya</FirstName>
        <LastName>Nurkalem</LastName>
      </Author>
      <Author>
        <FirstName>Dursun</FirstName>
        <LastName>Duman</LastName>
      </Author>
    </AuthorList>
    <PublicationType>Journal Article</PublicationType>
    <ArticleIdList>
      <ArticleId IdType="doi">10.34172/jcvtr.2020.51</ArticleId>
    </ArticleIdList>
    <History>
      <PubDate PubStatus="received">
        <Year>2020</Year>
        <Month>07</Month>
        <Day>29</Day>
      </PubDate>
      <PubDate PubStatus="accepted">
        <Year>2020</Year>
        <Month>11</Month>
        <Day>13</Day>
      </PubDate>
    </History>
    <Abstract>Introduction: The aim of this study was to evaluate the in-hospital and short-term predictive factors of mortality in intermediate-high risk acute pulmonary embolism (PE) patients with right ventricle (RV)dysfunction and myocardial injury. Methods: In this retrospective study, the medical records of 187 patients with a diagnosis of intermediate high risk acute PE were evaluated. A contrast-enhanced multi-detector pulmonary angiography was used to confirm diagnosis in all cases. All-cause mortality was determined by obtaining both in hospital and 30 days follow-up data of patients from medical records. Results: During the in-hospital stay (9.5±4.72 days), 7 patients died, resulting in an acute PE related in-hospital mortality of 3.2%. Admission heart rate (HR), (Odds ratio (OR), 1.028 95% Confidence interval (CI), 0.002-1.121; P = 0.048) and blood urea nitrogen (BUN) (OR, 1.028 95% CI, 0.002-1.016; P = 0.044) were found to be independent predictors for in-hospital mortality in a multi variate logistic regression analysis. In total, 32 patients (20.9%) died during 30 days follow-up.The presence of congestive heart failure (OR, 0.015, 95%CI, 0.001-0.211; P = 0.002) and dementia (OR, 0.029, 95%CI,0.002-0.516; P = 0.016) as well as low albumin level (OR, 0.049 95%CI, 0.006-0.383; P = 0.049) were associated with 30 days mortality. Conclusion: HR and BUN were independent predictors of in-hospital mortality and the presence of congestive heart failure, dementia, and low albumin levels were associated with higher 30 days mortality.</Abstract>
    <ObjectList>
      <Object Type="keyword">
        <Param Name="value">Acute Pulmonary Embolism</Param>
      </Object>
      <Object Type="keyword">
        <Param Name="value">Mortality</Param>
      </Object>
      <Object Type="keyword">
        <Param Name="value">Intermediate-High Risk</Param>
      </Object>
    </ObjectList>
  </Article>
</ArticleSet>