Tabriz University of Medical Sciences Journal of Cardiovascular and Thoracic Research 2008-5117 15 2 2023 06 29 Association of the high-sensitive cardiac troponin T levels and long-term mortality in patients with acute aortic dissection type A 116 120 10.34172/jcvtr.2023.31624 EN Yaser Jenab https://orcid.org/0000-0002-8291-8637 Seyed-Hossein Ahmadi-Tafti https://orcid.org/0000-0003-1040-4941 Tahereh Davarpasand https://orcid.org/0000-0003-0544-4009 Arash Jalali https://orcid.org/0000-0003-3225-8498 Hamid Khederlou https://orcid.org/0000-0001-8606-2381 Journal Article 10.34172/jcvtr.2023.31624 2022 08 19 2023 05 21 Introduction: Acute aortic dissection type A is a life-threatening cardiovascular emergency necessitating rapid diagnosis and treatment. We sought a new prognostic tool with cardiac biomarkers and simple inflammatory factors. Methods: from 2003 to 2014, 50 patients with documented acute aortic dissection type A were entered to this study. These patients were followed up until December 2020; within median follow up of 93.6 months. The patients were evaluated on the association of the baseline characteristics, first laboratory investigation, echocardiographic findings, surgical approach, and long-term mortality. Results: Total number of mortality during the follow up was 29 (58%) patients, which was significantly higher in medical group (89.4% vs 38.7%, P value=0.001). Multivariable analysis showed only an increase in hs-cTnT levels was suggested as a predictor of mortality (95% CI: 1.06–1.38; HR=1.21; P=0.005), so that for every 100 units increase, patients were 21% more likely to have mortality in long term. Also, performing surgical treatment for aortic dissection was determined as the independent predictor of surviving, so that death was 74.6% less than those who received medical treatment (95% CI: 0.13–0.58; HR=0.27; P=0.001). Conclusion: hs-cTnT is a potential predictor of mortality in patients with acute aortic dissection type A.