Submitted: 27 Jun 2016
Revision: 04 Jan 2017
Accepted: 04 Jan 2017
ePublished: 14 Jan 2017
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J Cardiovasc Thorac Res. 2016;8(4): 188-189.
doi: 10.15171/jcvtr.2016.37
PMID: 28210476
PMCID: PMC5304103
  Abstract View: 1037
  PDF Download: 709

Case Report

Left ventricular non-compaction in a patient with ankylosing spondylitis

Mehrnoush Toufan 1, Leili Pourafkari 1,2, Nader D Nader 2 *

1 Cardiovascular Research Center, Tabriz University of Medical Sciences,Tabriz, Iran
2 University at Buffalo, Buffalo, New York, 14214, USA


A 58 years old male with a long-standing history of HLA-B27 positive ankylosing spondylitis presented with increasing fatigue and dyspnea on exertion. He had left ventricular dysfunction and enlargement, flail right coronary leaflet of aortic valve with severe eccentric aortic insufficiency along with left ventricular non-compaction in echocardiography. The most common cardiac manifestations of ankylosing spondylitis are aortic insufficiency and conduction disturbances. Involvement of myocardium, in the form of dilated cardiomyopathy and restrictive cardiomyopathy, has also been reported. This case presents a very rare association of ankylosing spondylitis with non-compaction cardiomyopathy.
Keywords: Ankylosing Spondylitis, Noncompaction Cardiomyopathy, Aortic Valve
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