Submitted: 02 Sep 2019
Revision: 04 Aug 2020
Accepted: 11 Aug 2020
ePublished: 25 Aug 2020
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J Cardiovasc Thorac Res. 2020;12(3): 172-178.
doi: 10.34172/jcvtr.2020.30
  Abstract View: 98
  PDF Download: 113

Original Article

Presence of ear lobe crease may predict intermediate and high-risk patients with acute non-ST elevation acute coronary syndrome

Muzaffer Kahyaoglu 1* ORCID logo, Cetin Gecmen 2, Ozkan Candan 2, Murat Gucun 2, Ahmet Karaduman 2, Ahmet Guner 2, Ender Ozgun Cakmak 2, Emrah Bayam 3, Yusuf Yilmaz 3, Mehmet Celik 2, Ibrahim Akin Izgi 2

1 Gaziantep Abdulkadir Yuksel State Hospital, Gaziantep, Turkey
2 Kartal Kosuyolu Heart and Research Hospital, Istanbul, Turkey
3 Umraniye Education and Research Hospital, Istanbul, Turkey
*Corresponding Author: Muzaffer Kahyaoglu, Email: mkahyaoglu09@hotmail.com


Introduction: Ear lobe crease (ELC) was first described in 1973 as a physical examination finding indicating significant coronary artery disease (CAD). Several studies have been carried out in relation to this finding, and it has been shown that it is a marker of intima-media thickness, carotid artery disease, and CAD. We aimed to investigate the relationship between earlobe crease, which is a simple physical examination finding, and GRACE score as a risk estimation index in acute coronary syndromes without ST-segment elevation (NSTE-ACS) patients.
Methods: 360 patients (mean age 62.2 years, 70% male) were included in our study. Patients were divided into two groups of GRACE scores ≤ 109 and >109, 167 patients were enrolled in group 1, and193 cases in group 2.
Results: The group 2 patients were older, had higher systolic blood pressure (SBP) levels, a higher rate of hypertension, higher glucose levels, lower creatinine clearance levels, higher initial and peak troponin levels, lower hemoglobin levels, lower left ventricular ejection fraction (LVEF) and higher Gensini scores than the patients in group 1. The higher GRACE score group had markedly increased frequencies of ELC compared to the lower GRACE score group (80.8% vs. 24.5%, respectively, P < 0.001).
Conclusion: The presence of ELC may predict moderate to high risk group of patients with NSTEACS.

Keywords: Ear Lobe Crease, GRACE Score, NSTE-ACS
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