Submitted: 23 Apr 2020
Revision: 13 Jul 2020
Accepted: 03 Aug 2020
ePublished: 26 Aug 2020
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J Cardiovasc Thorac Res. 2020;12(3): 222-226.
doi: 10.34172/jcvtr.2020.38
  Abstract View: 64
  PDF Download: 91

Short Communication

Early results of the Resilia Inspiris aortic valve in the old age patients - a retrospective comparison with the Carpentier Edwards Magna Ease

Magjun Shala 1 ORCID logo, Lars Niclauss 1,2* ORCID logo

1 Faculty of Medicine and Biology, Lausanne University, Lausanne, Switzerland
2 Cardiovascular Department, Division of Cardiovascular Surgery, University Hospital Lausanne (CHUV), Lausanne, Switzerland
*Corresponding Author: Lars Niclauss, Email: lars.niclauss@chuv.ch


Introduction: The Inspiris Resilia aortic valve® (INSPIRIS) is a pericardial bio-prosthesis with a new sterilization procedure that shows promising results in terms of reduced calcification.
Methods: The 30-day mortality and morbidity were analyzed, comparing the INSPIRIS implanted between May 2017 and the end of January 2019, with its “predecessor”, the Carpentier-Edwards Perimound Magna Ease (ME). Echocardiography was performed one-week after surgery. 125consecutively operated patients were included (59 INSPIRIS, 66 ME).
Results: One patient in the ME group died and one patient in the INSPIRIS group had a complicated postoperative course due to right heart failure. Two patients (one INSPIRIS, one ME patient) suffered a perioperative stroke. The hemodynamic evaluation shows an effective reduction of mean transvalvular pressure gradients after surgery in both groups. INSPIRIS tended to have lower trans-prosthetic pressure gradients (9 mm Hg, Interquartile range [IQR] 11-7 mm Hg versus 12 mm Hg, IQR 15-9 mmHg; P = 0.001), reduced trans-prosthetic blood flow acceleration (209 cm/s, IQR 220-190 cm/s versus227 cm/s, IQR 263-191 cm/s; P = 0.003) and increased permeability indices (57%, IQR 67%- 47% versus42%, IQR 48%-38%; P8%; P < 0.001).
Conclusion: There are only few clinical data available from INSPIRIS, and the present analysis confirms good results initial postoperatively with a tendency towards possibly improved hemodynamics compared to ME.
Keywords: Surgical Aortic Valve Replacement, Inspiris Resilia Aortic Valve, Tissue Preservation, Bioprosthetic Aortic Valve, Hemodynamics
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