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Submitted: 23 Dec 2023
Accepted: 19 Jul 2024
ePublished: 20 Sep 2024
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J Cardiovasc Thorac Res. 2024;16(3): 194-197.
doi: 10.34172/jcvtr.33062
PMID: 39430283
PMCID: PMC11489635
  Abstract View: 160
  PDF Download: 153

Short Communication

The effects of digoxin on heart failure mortality and re-admission in a single center cross-sectional study

Mahsa Behnemoon 1* ORCID logo, Zahra Borumandkia 2 ORCID logo

1 Department of Cardiology, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran
2 Medical Center, Urmia University of Medical Sciences, Urmia, Iran
*Corresponding Author: Mahsa Behnemoon, Email: behnamoon.mahsa870@gmail.com

Abstract

Introduction: Mortality benefit of digoxin prescription in patients suffering from heart failure has been questioned many time. We evaluated these effects among admitted symptomatic heart failure patients.

Methods: We retrospectively divided our patients into two groups: group A (n=205) were digoxin prescribed, and group B (n=96) were digoxin naïve patients. Both groups’ medical records were gathered for one year, and the study endpoints were compared between the two groups.

Results: The mean age was 62.3±12.1 years and 54.8 % were male. All-cause mortality and readmission occurred in 26.7% and 31.7% of individuals, respectively, without significant differences between the two groups. However, in subgroup analysis, there was a significant relationship between in-hospital mortality and the presence of cardiovascular risk factors.

Conclusion: Digoxin might increase in-hospital mortality in patients with underlying cardiovascular risk factors.

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