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Submitted: 30 May 2020
Revision: 27 Oct 2020
Accepted: 02 Nov 2020
ePublished: 23 Dec 2020
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  Abstract View: 25

Review Article

Coagulopathy: Another side effect of coronavirus infection

Fatemeh Sadoughi, Parisa Maleki Dana, Jamal Hallajzadeh* ORCID logo, Zatollah Asemi* ORCID logo, Mohammad Ali Mansournia, Bahman Yousefi

Abstract

Recently, coronavirus disease 2019 (COVID-19) has been considered as a major health problem around the globe. This severe acute respiratory syndrome has a bunch of features, such as high transmission rate, which are adding to its importance. Overcoming this disease relies on a complete understanding of the viral structure, receptors, at-risk cells or tissues, and pathogenesis. Currently, researches have shown that besides the lack of a proper anti-viral therapeutic method,complications provided by this virus are also standing in the way of decreasing its mortality rate. One of these complications is believed to be a hematologic manifestation. Commonly,three kinds of coagulopathies are detected in COVID-19 patients: disseminated intravascular coagulation (DIC), pulmonary embolism (PE), and deep vein thrombosis (DVT). In this paper,we have reviewed the relation between these conditions and coronavirus-related diseases pathogenesis, severity, and mortality rate.
Keywords: SARS, COVID-19, CoV, Heparin, DIC, PIC, VTE
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