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J Cardiovasc Thorac Res. 2017;9(2): 102-107. doi: 10.15171/jcvtr.2017.17
PMID: 28740630        PMCID: PMC5516049

Original Article

Safety and effect of high dose allopurinol in patients with severe left ventricular systolic dysfunction

Mohammad Mostafa Ansari-Ramandi 1, Majid Maleki 1, Azin Alizadehasl 1, Ahmad Amin 1, Sepideh Taghavi 1, Mohammad Javad Alemzadeh-Ansari 1, Ali Kazem Moussavi 1, Nasim Naderi 1 *

Cited by CrossRef: 13

1- Angelini A, Pi X, Xie L. Dioxygen and Metabolism; Dangerous Liaisons in Cardiac Function and Disease. Front Physiol. 2017;8 [Crossref]
2- Tsigkou V, Oikonomou E, Anastasiou A, Lampsas S, Zakynthinos G, Kalogeras K, Katsioupa M, Kapsali M, Kourampi I, Pesiridis T, Marinos G, Vavuranakis M, Tousoulis D, Vavuranakis M, Siasos G. Molecular Mechanisms and Therapeutic Implications of Endothelial Dysfunction in Patients with Heart Failure. IJMS. 2023;24(5):4321 [Crossref]
3- Mirtajaddini M, Amin A, Naderi N, Taghavi S. The Correlation Between Uric Acid Level and Right Heart Catheterization Findings in Pulmonary Hypertension. Multidiscip Cardio Annal. 2019;10(2) [Crossref]
4- Zhou X, Liu T, Xu B, Zhang W, Li X, Wei F, Lv H, Ji X, Zhang B, Wang S. Dandelion Leaf Aqueous Extract Relieves Hyperuricemia and Its Complications via Modulating Uric Acid Metabolism, Renal Inflammation, and Gut Microbes. Foods. 2025;14(22):3843 [Crossref]
5- Allopurinol. Reactions Weekly. 2017;1667(1):19 [Crossref]
6- Simpson C, Damico R, Hummers L, Khair R, Kolb T, Hassoun P, Mathai S. Serum uric acid as a marker of disease risk, severity, and survival in systemic sclerosis‐related pulmonary arterial hypertension. Pulm circ. 2019;9(3):1 [Crossref]
7- Nandi S, Panda A, Chakraborty A, Rathee S, Roy I, Barik S, Mohapatra S, Biswas A. Role of ATP-Small Heat Shock Protein Interaction in Human Diseases. Front Mol Biosci. 2022;9 [Crossref]
8- Liu N, Wang Y, Yang M, Bian W, Zeng L, Yin S, Xiong Z, Hu Y, Wang S, Meng B, Sun J, Yang X. New Rice-Derived Short Peptide Potently Alleviated Hyperuricemia Induced by Potassium Oxonate in Rats. J Agric Food Chem. 2019;67(1):220 [Crossref]
9- Han J, Wang X, Tang S, Lu C, Wan H, Zhou J, Li Y, Ming T, Wang Z, Su X. Protective effects of tuna meat oligopeptides (TMOP) supplementation on hyperuricemia and associated renal inflammation mediated by gut microbiota. The FASEB Journal. 2020;34(4):5061 [Crossref]
10- Fan S, Huang Y, Lu G, Sun N, Wang R, Lu C, Ding L, Han J, Zhou J, Li Y, Ming T, Su X. Novel anti-hyperuricemic hexapeptides derived fromApostichopus japonicushydrolysate and their modulation effects on the gut microbiota and host microRNA profile. Food Funct. 2022;13(7):3865 [Crossref]
11- Kanbay M, Afsar B, Siriopol D, Dincer N, Erden N, Yilmaz O, Sag A, Kuwabara M, Cherney D, Rossignol P, Ortiz A, Covic A. Effect of Uric Acid-Lowering Agents on Cardiovascular Outcome in Patients With Heart Failure: A Systematic Review and Meta-Analysis of Clinical Studies. Angiology. 2020;71(4):315 [Crossref]
12- Siemińska E, Sobczak P, Skibińska N, Sikora J. The differential role of uric acid – The purpose or cause of cardiovascular diseases?. Medical Hypotheses. 2020;142:109791 [Crossref]
13- Karev E, Verbilo S, Malev E, Prokudina M. The impact of medical therapy on left ventricular strain: Current state and future perspectives. J of Clinical Ultrasound. 2022;50(7):887 [Crossref]
14- Johnson T, Jinnah H, Kamatani N. Shortage of Cellular ATP as a Cause of Diseases and Strategies to Enhance ATP. Front Pharmacol. 2019;10 [Crossref]
15- Qin S, Xiang M, Gao L, Cheng X, Zhang D. Uric Acid is a Biomarker for Heart Failure, but Not Therapeutic Target: Result from a Comprehensive Meta-Analysis. 2024;11(1):78 [Crossref]