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J Cardiovasc Thorac Res. 2018;10(4): 203-208. doi: 10.15171/jcvtr.2018.35
PMID: 30680078        PMCID: PMC6335985

Original Article

Decreasing serum homocysteine and hypocholesterolemic effects of bovine lactoferrin in male rat fed with high-cholesterol diet

Samira Nozari 1,2,3, Nazila Fathi Maroufi 4, Mohammad Nouri 1,3 * , Mirhamid Paytakhti Oskouei 4, Javad Shiralizade 5, Farshid Yekani 6, Mina Mamipour 1, Yousef Faridvand 1,3,7,8 *

Cited by CrossRef: 8


1- Faridvand Y, Nozari S, Asoudeh-Fard A, Karimi M, Pezeshkian M, Safaie N, Nouri M. Bovine lactoferrin ameliorates antioxidant esterase activity and 8-isoprostane levels in high-cholesterol-diet fed rats. International Journal for Vitamin and Nutrition Research. 2017;87(3-4):201 [Crossref]
2- Radagdam S, Asoudeh-Fard A, Karimi M, Faridvand Y, Gholinejad Z, Gerayesh Nejad S. Calcitriol modulates cholesteryl ester transfer protein (CETP) levels and lipid profile in hypercholesterolemic male rabbits: A pilot study. International Journal for Vitamin and Nutrition Research. 2021;91(3-4):212 [Crossref]
3- YILDIRIM G, BOZKURT A, ÖRKMEZ M, ULUSAL H. Effect of lactoferrin in rats fed with a high-fat diet and with a full-thickness skin defect model. 2023;48(4):1396 [Crossref]
4- Omiya K, Nakadate Y, Oguchi T, Sato T, Matsuoka T, Abe M, Kawakami A, Matsukawa T, Sato H. Cardioprotective effects of enteral vs. parenteral lactoferrin administration on myocardial ischemia-reperfusion injury in a rat model of stunned myocardium. BMC Pharmacol Toxicol. 2022;23(1) [Crossref]
5- Ianiro G, Niro A, Rosa L, Valenti P, Musci G, Cutone A. To Boost or to Reset: The Role of Lactoferrin in Energy Metabolism. IJMS. 2023;24(21):15925 [Crossref]
6- Nemati M, Akseh S, Amiri M, Reza Nejabati H, Jodati A, Fathi Maroufi N, Faridvand Y, Nouri M. Lactoferrin suppresses LPS-induced expression of HMGB1, microRNA 155, 146, and TLR4/MyD88/NF-кB pathway in RAW264.7 cells. Immunopharmacology and Immunotoxicology. 2021;43(2):153 [Crossref]
7- Chen C, Lu M, Zhang Z, Qin L. The role of lactoferrin in atherosclerosis. Biometals. 2023;36(3):509 [Crossref]
8- Soliman M, El-Kamel A, Shehat M, Bakr B, El-Moslemany R. Lactoferrin decorated bilosomes for the oral delivery of quercetin in type 2 diabetes: In vitro and in vivo appraisal. International Journal of Pharmaceutics. 2023;647:123551 [Crossref]
9- Ling C, Xu J, Li Y, Tong X, Yang H, Yang J, Yuan L, Qin L. Lactoferrin promotes bile acid metabolism and reduces hepatic cholesterol deposition by inhibiting the farnesoid X receptor (FXR)-mediated enterohepatic axis. Food Funct. 2019;10(11):7299 [Crossref]
10- Omiya K, Nakadate Y, Sato H, Oguchi T, Matsuoka T, Kawakami A, Schricker T, Matsukawa T. Role of the protein kinase A signaling pathway and identification of mediators in the cardioprotective effects of enteral lactoferrin for ischemia-reperfusion injury in an isolated rat heart model. Nutrition. 2023;113:112088 [Crossref]
11- Jańczuk A, Brodziak A, Czernecki T, Król J. Lactoferrin—The Health-Promoting Properties and Contemporary Application with Genetic Aspects. Foods. 2022;12(1):70 [Crossref]