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Platinum Open Access

This Platinum Open Access journal publishes articles totally free of charge for the authors and provides unrestricted access to the published content through its website and open access repositories such as PubMed Central. All related costs for processing of the manuscripts are sponsored by Tabriz University of Medical Sciences.

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J Cardiovasc Thorac Res. 2018;10(4): 203-208. doi: 10.15171/jcvtr.2018.35

PMID: 30680078 PMCID: PMC6335985

Original Article

Decreasing serum homocysteine and hypocholesterolemic effects of bovine lactoferrin in male rat fed with high-cholesterol diet

Samira Nozari ^1,2,3, Nazila Fathi Maroufi ⁴, Mohammad Nouri ^1,3 * , Mirhamid Paytakhti Oskouei ⁴, Javad Shiralizade ⁵, Farshid Yekani ⁶, Mina Mamipour ¹, Yousef Faridvand ^1,3,7,8 *

Cited by CrossRef: 8

1- Faridvand Y, Nozari S, Asoudeh-Fard A, Karimi M, Pezeshkian M, Safaie N, Nouri M. Bovine lactoferrin ameliorates antioxidant esterase activity and 8-isoprostane levels in high-cholesterol-diet fed rats. International Journal for Vitamin and Nutrition Research. 2017;87(3-4):201 [Crossref]

2- Radagdam S, Asoudeh-Fard A, Karimi M, Faridvand Y, Gholinejad Z, Gerayesh Nejad S. Calcitriol modulates cholesteryl ester transfer protein (CETP) levels and lipid profile in hypercholesterolemic male rabbits: A pilot study. International Journal for Vitamin and Nutrition Research. 2021;91(3-4):212 [Crossref]

3- YILDIRIM G, BOZKURT A, ÖRKMEZ M, ULUSAL H. Effect of lactoferrin in rats fed with a high-fat diet and with a full-thickness skin defect model. 2023;48(4):1396 [Crossref]

4- Omiya K, Nakadate Y, Oguchi T, Sato T, Matsuoka T, Abe M, Kawakami A, Matsukawa T, Sato H. Cardioprotective effects of enteral vs. parenteral lactoferrin administration on myocardial ischemia-reperfusion injury in a rat model of stunned myocardium. BMC Pharmacol Toxicol. 2022;23(1) [Crossref]

5- Ianiro G, Niro A, Rosa L, Valenti P, Musci G, Cutone A. To Boost or to Reset: The Role of Lactoferrin in Energy Metabolism. IJMS. 2023;24(21):15925 [Crossref]

6- Nemati M, Akseh S, Amiri M, Reza Nejabati H, Jodati A, Fathi Maroufi N, Faridvand Y, Nouri M. Lactoferrin suppresses LPS-induced expression of HMGB1, microRNA 155, 146, and TLR4/MyD88/NF-кB pathway in RAW264.7 cells. Immunopharmacology and Immunotoxicology. 2021;43(2):153 [Crossref]

7- Chen C, Lu M, Zhang Z, Qin L. The role of lactoferrin in atherosclerosis. Biometals. 2023;36(3):509 [Crossref]

8- Soliman M, El-Kamel A, Shehat M, Bakr B, El-Moslemany R. Lactoferrin decorated bilosomes for the oral delivery of quercetin in type 2 diabetes: In vitro and in vivo appraisal. International Journal of Pharmaceutics. 2023;647:123551 [Crossref]

9- Ling C, Xu J, Li Y, Tong X, Yang H, Yang J, Yuan L, Qin L. Lactoferrin promotes bile acid metabolism and reduces hepatic cholesterol deposition by inhibiting the farnesoid X receptor (FXR)-mediated enterohepatic axis. Food Funct. 2019;10(11):7299 [Crossref]

10- Omiya K, Nakadate Y, Sato H, Oguchi T, Matsuoka T, Kawakami A, Schricker T, Matsukawa T. Role of the protein kinase A signaling pathway and identification of mediators in the cardioprotective effects of enteral lactoferrin for ischemia-reperfusion injury in an isolated rat heart model. Nutrition. 2023;113:112088 [Crossref]

11- Jańczuk A, Brodziak A, Czernecki T, Król J. Lactoferrin—The Health-Promoting Properties and Contemporary Application with Genetic Aspects. Foods. 2022;12(1):70 [Crossref]