Submit Your Paper Instructions for Authors Instructions for Reviewers Editor in Chief Editorial Board Editorial Policies English Editing Service Indexing and Abstracting Archive

Platinum Open Access

This Platinum Open Access journal publishes articles totally free of charge for the authors and provides unrestricted access to the published content through its website and open access repositories such as PubMed Central. All related costs for processing of the manuscripts are sponsored by Tabriz University of Medical Sciences.

Indexing Info

Collaborator of

J Cardiovasc Thorac Res. 2019;11(3): 189-195. doi: 10.15171/jcvtr.2019.32

PMID: 31579458 PMCID: PMC6759611

Original Article

Chronic dosing with metformin plus bosentan decreases in vitro pulmonary artery contraction from isolated arteries in adults with pulmonary hypertension

Shutan Liao ^1,2 , Dongsheng Li ³, Zheng Hui ², Craig S McLachlan ¹, Yang Zhang ³ *

Cited by CrossRef: 8

1- Bu Y, Peng M, Tang X, Xu X, Wu Y, Chen A, Yang X. Protective effects of metformin in various cardiovascular diseases: Clinical evidence and AMPK‐dependent mechanisms. J Cellular Molecular Medi. 2022;26(19):4886 [Crossref]

2- Xiao F, Zhang R, Wang L. Inhibitors of Mitochondrial Dynamics Mediated by Dynamin-Related Protein 1 in Pulmonary Arterial Hypertension. Front Cell Dev Biol. 2022;10 [Crossref]

3- Zhao Q, Song P, Zou M. AMPK and Pulmonary Hypertension: Crossroads Between Vasoconstriction and Vascular Remodeling. Front Cell Dev Biol. 2021;9 [Crossref]

4- António T, Soares-da-Silva P, Pires N, Gomes P. Salt-inducible kinases: new players in pulmonary arterial hypertension?. Trends in Pharmacological Sciences. 2022;43(10):806 [Crossref]

5- Hou J, Nie Y, Wen Y, Hua S, Hou Y, He H, Sun S. The role and mechanism of AMPK in pulmonary hypertension. Ther Adv Respir Dis. 2024;18 [Crossref]

6- Yang Y, Lin F, Xiao Z, Sun B, Wei Z, Liu B, Xue L, Xiong C. Investigational pharmacotherapy and immunotherapy of pulmonary arterial hypertension: An update. Biomedicine & Pharmacotherapy. 2020;129:110355 [Crossref]

7- Liu R, Yuan T, Wang R, Gong D, Wang S, Du G, Fang L. Insights into Endothelin Receptors in Pulmonary Hypertension. IJMS. 2023;24(12):10206 [Crossref]

8- Abdelazeem H, Tu L, Thuillet R, Ottaviani M, Boulfrad A, Beck T, Senbel A, Mani S, Castier Y, Guyard A, Tran-Dinh A, El-Benna J, Longrois D, Silverstein A, Guignabert C, Norel X. AMPK activation by metformin protects against pulmonary hypertension in rats and relaxes isolated human pulmonary artery. European Journal of Pharmacology. 2023;946:175579 [Crossref]

9- Abdelazeem H, Tu L, Thuillet R, Ottaviani M, Boulfrad A, Senbel A, Mani S, Castier Y, Guyard A, Tran-Dinh A, El-Benna J, Longrois D, Silverstein A, Guignabert C, Norel X. AMPK Activation Protects Against Pulmonary Hypertension in Rats and Relaxes Isolated Human Pulmonary Artery. SSRN Journal. 2022; [Crossref]