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J Cardiovasc Thorac Res. 2021;13(1): 54-60. doi: 10.34172/jcvtr.2021.18
PMID: 33815703        PMCID: PMC8007896

Original Article

Evaluation of iron overload by cardiac and liver T2* in β-thalassemia: Correlation with serum ferritin, heart function and liver enzymes

Hengameh Khadivi Heris 1 ORCID, Babak Nejati 2, Khatereh Rezazadeh 3, Hossein Sate 4, Roya Dolatkhah 2, Zohreh Ghoreishi 5, Ali Esfahani 2 * ORCID

Cited by CrossRef: 4


1- Xu F, Li D, Tang C, Liang B, Guan K, Liu R, Peng P. Magnetic resonance imaging assessment of the changes of cardiac and hepatic iron load in thalassemia patients before and after hematopoietic stem cell transplantation. Sci Rep. 2023;13(1) [Crossref]
2- Mohamed H, EL-Afifi A, Nabih N, Mohamed E, El-Razzaz M. Assessment of Serum Autophagy Related Protein Beclin-1 in Egyptian Adult Beta Thalassemia Patients. Indian J Hematol Blood Transfus. 2024; [Crossref]
3- Xu F, Peng Y, Xie H, Liang B, Yang G, Zhao F, Liu Y, Peng P. A multicenter study on the quantification of liver iron concentration in thalassemia patients by means of the MRI T2* technique. Front Med. 2023;10 [Crossref]
4- Chen Z, Liu R, Huang J, Mo J, Zeng Y, Huang Y, Yang L. Genotype Distribution and Clinical Characteristics of Thalassemia Patients Needing Transfusion in Yangjiang, Western Guangdong. Transfus Med Hemother. 2024;:1 [Crossref]
5- Güzelbey T, Gürses B, Sarsılmaz A, Karasu E, Özveren O, Aydın Y. Talasemi Majör Hastalarında MRG ile Kardiyak Demir Yükü Ölçümü, Demir Yükünün Kardiyak Fonksiyonlara Etkisinin Değerlendirilmesi ve Doku Doppleri ile Karşılaştırılması. 2024;(22):81 [Crossref]
6- Ibraheem A, Al Tameemi W. Impact of Empagliflozin on the Outcomes of β-Thalassemia Major in Patients With Type 2 Diabetes Mellitus: The THALEMPA Observational Study. 2024; [Crossref]
7- Saadatifar H, Mard-Soltani M, Niayeshfar A, Shakerian N, Pouriamehr S, Alinezhad Dezfuli D, Khalili S, Saadatifar S, Mashhadi S. Correlation between plasma biochemical parameters and cardio-hepatic iron deposition in thalassemia major patients. Scandinavian Journal of Clinical and Laboratory Investigation. 2024;84(4):245 [Crossref]
8- Meloni A, Pistoia L, Ricchi P, Longo F, Cecinati V, Sorrentino F, Borsellino Z, Bagnato S, Rossi V, Fina P, Riva A, Renne S, Peritore G, Positano V, Cademartiri F. Magnetic Resonance Evaluation of Tissue Iron Deposition and Cardiac Function in Adult Regularly Transfused Thalassemia Intermedia Compared with Thalassemia Major Patients. JCM. 2024;13(16):4791 [Crossref]
9- Bahmani Jahromi M, Hassani A, Kasaei M, Hooshanginezhad Z, Aslani A, Zekavat O, Mortezaie M, Khosropanah S. Evaluation of the efficacy of signal-averaged electrocardiogram testing in the cardiac assessment of beta-thalassemia major patients. BMC Cardiovasc Disord. 2022;22(1) [Crossref]
10- Alaqidi A, Al-Mamoori H. Unveiling the molecular and comorbidity profile among transfusion-dependent and nontransfusion-dependent beta-thalassemic patients in Baghdad city. 2024;13(2):223 [Crossref]
11- Lan X, Ye Z, Du J, Liu L, Tian C, Huang L, Mo X. Cross-sectional study on the impact of cardiac and hepatic iron overload, as measured by MRI T2*, on the quality of life in children with severe beta-thalassemia major. 2024;103(27):e38817 [Crossref]
12- Xu F, Luo C, Li M, Guan K, Peng F, Yang G, Peng P. Quantification of cardiac iron in patients with thalassemia with 3-T MRI calibrated by 1.5-T MRI. Acta Radiol. 2023;64(6):2096 [Crossref]
13- Mohammadi S, Jalilian M, Absalan F, Maghsoudi F, Samimi Z. Investigating the Relationship Between Liver and Heart Iron Overload Measured by T2 ⃰ Magnetic Resonance Imaging with Serum Ferritin Level, Liver Enzyme Ratio (Aspartate Aminotransferase / Alanine Aminotransferase) and Electrocardiography Findings in Patients with Thalassemia Major. Compr Health Biomed Stud. 2024;2(4) [Crossref]
14- Houshmand G, Parsaee M, Najmafshar L, Rajablou N, Golroudbari H, Hosseini R, Omidi N. Role of feature tracking cardiac magnetic resonance imaging in early detection of cardiac dysfunction in β‐thalassemia patients recovered from COVID‐19: A cross‐sectional study. Health Science Reports. 2024;7(1) [Crossref]
15- Xu F, Yi J, Tang C, Luo C, Peng P. A confirmatory study of the calibration formula between liver iron concentration (LIC) and R2* values in thalassemia patients. Chin J Acad Radiol. 2023;6(2):65 [Crossref]